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This is a historical photograph of the Union Depot (also called the CB&Q or Chicago, Burlington & Quincy Railroad depot) in Quincy, Illinois, dated 1895. 
The handwritten caption on the mount reads “Union Depot, Quincy, Ill. 1895.” The building itself has a prominent “QUINCY” sign on the gable end facing the camera. It is a long, single-story structure with a gabled roof, multiple chimneys, arched openings (some with hanging lamps), and a covered platform area extending along the side. A person stands near one of the large arched doorways, and a railroad car (or similar equipment) is visible to the left. The image is a classic late-19th-century albumen or similar print mounted on a textured card, typical of the period. 
Historical context
• This was the second major passenger depot in Quincy. The first small depot (associated with the Northern Cross / early Quincy & Chicago line) opened around 1856 near Front and Spring (or Front and Oak). The CB&Q replaced it with this larger facility in 1864–1865 on Front Street between Vermont and Broadway. Tracks ran through or alongside the west side of the building; it included offices, passenger waiting areas, mail facilities, and a refreshment room. 
• Quincy was an important Mississippi River rail hub. The CB&Q (one of the major Midwestern railroads, often called “the Q”) connected the city eastward toward Chicago and, after the 1868 bridge, westward into Missouri and beyond. By the 1870s Quincy was briefly Illinois’ second-largest city, and this depot handled significant passenger and freight traffic.
• A nearly identical view is held by the Quincy Public Library (Illinois Digital Archives) under the title “1865 Train Depot,” described as a street view of that depot taken about 1895. 
Later history
The 1864/65 depot was superseded by a larger CB&Q station at Second and Oak Streets that opened on July 31, 1899 (featuring a tall tower and more extensive facilities). That later station served until 1953, when passenger operations shifted to West Quincy, Missouri. The current Amtrak station in Quincy (opened 1985) is a modern facility unrelated to these earlier buildings. 
In short, you have a well-preserved period photograph of Quincy’s principal railroad passenger terminal during its heyday as a river-and-rail transportation center in the 1890s.
